SIP1 抗体 (C-Term)
Quick Overview for SIP1 抗体 (C-Term) (ABIN6991364)
抗原
See all SIP1 (GEMIN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- SIP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SIP1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human SIP1. The immunogen is located within the last 50 amino acids of SIP1.
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亚型
- IgG
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anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (C-Term) antibody
GEMIN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) antibodyGEMIN2 适用: 人 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 12-280) antibodyGEMIN2 适用: 人, 小鼠, 非洲爪蟾 WB, ELISA, IF, IP, ICC, FACS 宿主: 小鼠 Monoclonal 2E17 unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) antibodyGEMIN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) antibodyGEMIN2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 51-150) antibodyGEMIN2 适用: 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (Middle Region) antibodyGEMIN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (N-Term) antibodyGEMIN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (N-Term) antibodyGEMIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 35-84) antibodyGEMIN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig, 豚鼠, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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SIP1 antibody can be used for detection of SIP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 4 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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别名
- SIP1
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背景
- SIP1 Antibody: SIP1 is one of the proteins found in the SMN complex, which consists of the survival of motor neuron (SMN) protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. SIP1 interacts directly with the SMN and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. However, knockdown of the SIP1 mRNA in motor neurons showed normal motor axons while that of SMN mRNA did show abnormal motor axon outgrowth, indicating that SIP1 may have additional roles outside of the SMN complex.
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基因ID
- 8487
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UniProt
- O14893
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途径
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
抗原
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