FOXO4 抗体 (N-Term)
Quick Overview for FOXO4 抗体 (N-Term) (ABIN6991360)
抗原
See all FOXO4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-80, N-Term
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纯化方法
- FOXO4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- FOXO4 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FOXO4. The immunogen is located within amino acids 30 - 80 of FOXO4.
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亚型
- IgG
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anti-Forkhead Box O4 (FOXO4) (pSer197) antibody
FOXO4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (pThr451) antibodyFOXO4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (N-Term) antibodyFOXO4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (pSer197) antibodyFOXO4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (pSer197) antibodyFOXO4 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (C-Term) antibodyFOXO4 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (AA 45-63) antibodyFOXO4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (AA 206-240) antibodyFOXO4 适用: 人 WB, IF 宿主: 兔 Polyclonal RB51229 unconjugated
anti-Forkhead Box O4 (FOXO4) (Internal Region) antibodyVerified FOXO4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Forkhead Box O4 (FOXO4) (pSer197) antibodyFOXO4 适用: 人, 小鼠, 大鼠, 猴, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
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FOXO4 antibody can be used for detection of FOXO4 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- FOXO4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- FOXO4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FOXO4 (Forkhead Box O4 (FOXO4))
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别名
- FOXO4
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背景
- FOXO4 Antibody: FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.
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基因ID
- 4303
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NCBI登录号
- NP_005929
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UniProt
- P98177
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途径
- Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
抗原
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