SNRPE 抗体 (AA 330-380)
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北京 101111
Quick Overview for SNRPE 抗体 (AA 330-380) (ABIN6991349)
抗原
See all SNRPE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 330-380
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纯化方法
- B-raf Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-B-raf antibody was raised against a peptide corresponding to 18 amino acids near the center of human B-raf. The immunogen is located within amino acids 330 - 380 of B-raf.
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亚型
- IgY
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应用备注
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WB: 0.5-2 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- B-raf Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- B-raf antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SNRPE (Small Nuclear Ribonucleoprotein Polypeptide E (SNRPE))
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别名
- B-raf
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背景
- B-raf Antibody: B-raf belongs to the raf/mil family of serine/threonine protein kinases and plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. The Ras/Raf/MEK/ERK and Ras/PI3K/PTEN/Akt pathways interact with each other to regulate growth and in some cases tumorigenesis. Mutations in B-raf have been associated with several cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung, leading to speculation on the possibility of B-raf as a therapeutic target for treating cancers. Mutations in this gene have also been associated with cardiofaciocutaneous syndrome (CFCS), a disease characterized by heart defects, mental retardation and a distinctive facial appearance.
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分子量
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Predicted: 94kD
Observed: 94 kD kDa -
基因ID
- 673
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UniProt
- P15056
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途径
- Ribonucleoprotein Complex Subunit Organization, Hepatitis C
抗原
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