SIRT7 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for SIRT7 抗体 (N-Term) (ABIN6991348)
抗原
See all SIRT7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 50-100, N-Term
-
纯化方法
- SIRT7 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- SIRT7 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human SIRT7. The immunogen is located within amino acids 50 - 100 of SIRT7.
-
亚型
- IgY
-
-
-
-
应用备注
-
SIRT7 antibody can be used for detection of SIRT7 by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- SIRT7 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- SIRT7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- SIRT7 (Sirtuin 7 (SIRT7))
-
别名
- SIRT7
-
背景
- SIRT7 Antibody: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT7 is a nucleolar protein that positively regulates RNA polymerase I transcription and has been postulated to enable cells to sustain critical functions by inhibiting cell growth under severe stress conditions.
-
基因ID
- 51547
-
NCBI登录号
- NP_057622
-
UniProt
- Q9NRC8
抗原
-