ANAPC13 抗体
Quick Overview for ANAPC13 抗体 (ABIN6991331)
抗原
See all ANAPC13 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- APC13 Antibody is affinity chromatography purified via peptide column.
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免疫原
- APC13 antibody was raised against a 17 amino acid synthetic peptide near the center of human APC13. The immunogen is located within the last 50 amino acids of APC13.
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亚型
- IgG
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anti-Anaphase Promoting Complex Subunit 13 (ANAPC13) antibody
ANAPC13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 13 (ANAPC13) (Internal Region) antibodyANAPC13 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Anaphase Promoting Complex Subunit 13 (ANAPC13) (Center) antibodyANAPC13 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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APC13 antibody can be used for detection of APC13 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- APC13 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- APC13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))
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别名
- APC13
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背景
- APC13 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.
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分子量
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Predicted: 15 kDa
Observed: 14 kDa -
基因ID
- 25847
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NCBI登录号
- NP_056206
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UniProt
- Q9BS18
抗原
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