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APC1 抗体 (C-Term)

This anti-APC1 antibody is a 兔 多克隆 antibody detecting APC1 in ELISA, WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6991321
发货至: 中国

Quick Overview for APC1 抗体 (C-Term) (ABIN6991321)

抗原

See all APC1 (ANAPC1) 抗体
APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

适用

  • 50
  • 40
  • 23
人, 小鼠

宿主

  • 79
  • 2

克隆类型

  • 79
  • 2
多克隆

标记

  • 31
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APC1 antibody is un-conjugated

应用范围

  • 40
  • 40
  • 30
  • 14
  • 13
  • 13
  • 11
  • 10
  • 5
  • 5
  • 4
  • 2
  • 1
  • 1
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 26
    • 16
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1810-1860, C-Term

    纯化方法

    APC1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    APC1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human APC1. The immunogen is located within amino acids 1810 - 1860 of APC1.

    亚型

    IgG
  • 应用备注

    APC1 antibody can be used for detection of APC1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    APC1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    APC1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    APC1 (ANAPC1) (Anaphase Promoting Complex Subunit 1 (ANAPC1))

    别名

    APC1

    背景

    APC1 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC1, also known as mitotic checkpoint regulator (MCPR), is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex.

    基因ID

    64682

    UniProt

    Q9H1A4
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