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EFHD2 抗体 (N-Term)

This anti-EFHD2 antibody is a 兔 多克隆 antibody detecting EFHD2 in ELISA, WB, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6991298
发货至: 中国

Quick Overview for EFHD2 抗体 (N-Term) (ABIN6991298)

抗原

See all EFHD2 抗体
EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

适用

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人, 小鼠, 大鼠

宿主

  • 11
  • 1

克隆类型

  • 12
多克隆

标记

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This EFHD2 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 5
    • 3
    • 2
    • 1
    • 1
    N-Term

    纯化方法

    EFHD2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    EFHD2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human EFHD2. The immunogen is located within the first 50 amino acids of EFHD2.

    亚型

    IgG
  • 应用备注

    EFHD2 antibody can be used for detection of EFHD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    EFHD2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    EFHD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • ODonnell, Dagley, Curley, Darbey, OShaughnessy, Diemer, Pilatz, Fietz, Stanton, Smith, Rebourcet: "Sertoli cell-enriched proteins in mouse and human testicular interstitial fluid." in: PloS one, Vol. 18, Issue 9, pp. e0290846, (2023) (PubMed).

  • 抗原

    EFHD2 (EF-Hand Domain Family, Member D2 (EFHD2))

    别名

    EFHD2

    背景

    EFHD2 Antibody: EFHD2, also known as Swiprosin-1 or SWS1, is an EF-hand and coiled-coil-containing adaptor protein that plays a role in lymphocyte physiology. EFHD2 exhibits the highest expression in CD8+ T cells and immature B cells. It provides a membrane scaffold that is required for the Syk-, SLP-65-, and PLCgamma2-dependent B-cell receptor (BCR)-induced calcium flux. EFHD2 may also regulate BCR-induced immature and primary B-cell apoptosis. It controls spontaneous apoptosis through the regulation of BCL2L1 abundance. Also, EFHD2 plays a role as negative regulator of the canonical NF-κ,B-activating branch.

    基因ID

    79180

    NCBI登录号

    NP_077305

    UniProt

    Q96C19
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