LRRC19 抗体 (C-Term)
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北京 101111
Quick Overview for LRRC19 抗体 (C-Term) (ABIN6991292)
抗原
See all LRRC19 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 290-340, C-Term
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纯化方法
- LRRC19 Antibody is affinity chromatography purified via peptide column.
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免疫原
- LRRC19 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRC19. The immunogen is located within amino acids 290 - 340 of LRRC19.
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亚型
- IgG
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应用备注
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LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- LRRC19 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- LRRC19 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))
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别名
- LRRC19
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背景
- LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κ,B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.
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基因ID
- 64922
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NCBI登录号
- NP_075052
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UniProt
- Q9H756
抗原
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