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LRRC19 抗体 (C-Term)

This anti-LRRC19 antibody is a 兔 多克隆 antibody detecting LRRC19 in ELISA, WB, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6991292
发货至: 中国

Quick Overview for LRRC19 抗体 (C-Term) (ABIN6991292)

抗原

See all LRRC19 抗体
LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

适用

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人, 小鼠

宿主

  • 43

克隆类型

  • 43
多克隆

标记

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This LRRC19 antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    AA 290-340, C-Term

    纯化方法

    LRRC19 Antibody is affinity chromatography purified via peptide column.

    免疫原

    LRRC19 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRC19. The immunogen is located within amino acids 290 - 340 of LRRC19.

    亚型

    IgG
  • 应用备注

    LRRC19 antibody can be used for detection of LRRC19 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    LRRC19 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    LRRC19 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    LRRC19 (Leucine Rich Repeat Containing 19 (LRRC19))

    别名

    LRRC19

    背景

    LRRC19 Antibody: LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-κ,B and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.

    基因ID

    64922

    NCBI登录号

    NP_075052

    UniProt

    Q9H756
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