GATA3 抗体 (C-Term)
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北京 101111
Quick Overview for GATA3 抗体 (C-Term) (ABIN6991272)
抗原
See all GATA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 340-390, C-Term
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纯化方法
- GATA3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- GATA3 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GATA3. The immunogen is located within amino acids 340 - 390 of GATA3.
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亚型
- IgG
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应用备注
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GATA3 antibody can be used for detection of GATA3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GATA3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GATA3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- GATA3 (GATA Binding Protein 3 (GATA3))
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别名
- GATA3
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背景
- GATA3 Antibody: GATA3 is a zinc finger transcription factor that was first recognized as a possible determinant of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.
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分子量
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Predicted: 49 kDa
Observed: 49 kDa -
基因ID
- 2625
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NCBI登录号
- NP_001002295
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UniProt
- P23771
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途径
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
抗原
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