BFAR 抗体 (C-Term)
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北京 101111
Quick Overview for BFAR 抗体 (C-Term) (ABIN6991268)
抗原
See all BFAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 300-350, C-Term
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纯化方法
- BFAR Antibody is affinity chromatography purified via peptide column.
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免疫原
- BFAR antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human BFAR. The immunogen is located within amino acids 300 - 350 of BFAR.
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亚型
- IgG
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应用备注
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BFAR antibody can be used for detection of BFAR by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BFAR Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BFAR antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BFAR (Bifunctional Apoptosis Regulator (BFAR))
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别名
- BFAR
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背景
- BFAR Antibody: The bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival.
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基因ID
- 51283
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NCBI登录号
- NP_057645
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UniProt
- Q9NZS9
抗原
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