FAM212A antibody is human and mouse . At least two isoforms of FAM212A are known to exist, this antibody will recognize both isoforms.
纯化方法
FAM212A antibody is affinity chromatography purified via peptide column.
免疫原
FAM212A antibody was raised against a 15 amino acid peptide near the carboxy terminus of human FAM212A. The immunogen is located within the last 50 amino acids of FAM212A.
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背景
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives (1). FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics (1). In mammals, FAM212A is thought to play a role in neural tube closure, a significant fraction of FAM212A-null mice exhibited exencephaly (2).