RHBDD3 抗体 (AA 170-220)
The 兔 多克隆 anti-RHBDD3 antibody (ABIN6991242) specifically detects RHBDD3 in WB, ELISA 和 IF.
The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6991242
发货至:
中国
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Our Local Distributor
中国
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北京 101111
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Quick Overview for RHBDD3 抗体 (AA 170-220) (ABIN6991242)
抗原
RHBDD3
(Rhomboid Domain Containing 3 (RHBDD3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This RHBDD3 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF)
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抗原表位
- AA 170-220
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纯化方法
- RHBDD3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RHBDD3 antibody was raised against a 13 amino acid synthetic peptide from near the center of human RHBDD3. The immunogen is located within amino acids 170 - 220 of RHBDD3.
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亚型
- IgG
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anti-Rhomboid Domain Containing 3 (RHBDD3) (AA 304-323) antibody
RHBDD3 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Rhomboid Domain Containing 3 (RHBDD3) (Internal Region) antibodyRHBDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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RHBDD3 antibody can be used for detection of RHBDD3 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RHBDD3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RHBDD3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RHBDD3 (Rhomboid Domain Containing 3 (RHBDD3))
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别名
- RHBDD3
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背景
- RHBDD3 Antibody: The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD3 was initially identified as a novel pituitary tumor apoptosis gene (PTAG) whose expression was reduced in certain pituitary adenomas. Overexpression of RHBDD3 in AtT20 cells showed an increase in apoptotic activity and caspase activation in response to bromocriptine, and apoptosis-inducing dopamine D2 analog, suggesting that reactivation of RHBDD3 in tumors may be a therapeutically useful tool. Later experiments also showed that RHBDD3 expression is also reduced in several primary colorectal tumors, indicating that loss of RHBDD3 contributes to a blunted apoptotic response and probably predisposes cells towards malignant transformation.
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基因ID
- 25807
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NCBI登录号
- NP_036397
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UniProt
- Q9Y3P4
抗原
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