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SRPX 抗体 (N-Term)

The 兔 多克隆 anti-SRPX antibody is suitable to detect SRPX in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 IHC (p).
产品编号 ABIN6991220
发货至: 中国
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Quick Overview for SRPX 抗体 (N-Term) (ABIN6991220)

抗原

See all SRPX 抗体
SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

适用

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人, 小鼠, 大鼠

宿主

  • 39
  • 2

克隆类型

  • 41
多克隆

标记

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This SRPX antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 4
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    • 2
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    • 1
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    AA 30-80, N-Term

    纯化方法

    SRPX1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    SRPX1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1. The immunogen is located within amino acids 30 - 80 of SRPX1.

    亚型

    IgG
  • 应用备注

    SRPX1 antibody can be used for detection of SRPX1 by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SRPX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SRPX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

    别名

    SRPX1

    背景

    SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.

    基因ID

    8406

    NCBI登录号

    NP_006298

    UniProt

    P78539
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