SRPX 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for SRPX 抗体 (N-Term) (ABIN6991220)
抗原
See all SRPX 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 30-80, N-Term
-
纯化方法
- SRPX1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- SRPX1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1. The immunogen is located within amino acids 30 - 80 of SRPX1.
-
亚型
- IgG
-
-
-
-
应用备注
-
SRPX1 antibody can be used for detection of SRPX1 by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- SRPX1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- SRPX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))
-
别名
- SRPX1
-
背景
- SRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.
-
基因ID
- 8406
-
NCBI登录号
- NP_006298
-
UniProt
- P78539
抗原
-