FRMPD2 抗体 (N-Term)
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北京 101111
Quick Overview for FRMPD2 抗体 (N-Term) (ABIN6991212)
抗原
See all FRMPD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130, N-Term
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纯化方法
- FRMPD2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- FRMPD2 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human FRMPD2. The immunogen is located within amino acids 80 - 130 of FRMPD2.
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亚型
- IgG
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anti-FERM and PDZ Domain Containing 2 (FRMPD2) (AA 1-261) antibody
FRMPD2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FERM and PDZ Domain Containing 2 (FRMPD2) (N-Term) antibodyFRMPD2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-FERM and PDZ Domain Containing 2 (FRMPD2) (N-Term) antibodyFRMPD2 适用: 人, Cow, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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FRMPD2 antibody can be used for detection of FRMPD2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- FRMPD2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- FRMPD2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FRMPD2 (FERM and PDZ Domain Containing 2 (FRMPD2))
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别名
- FRMPD2
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背景
- FRMPD2 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD2 also contains an N-terminal KIND domain and three PDZ domains and is structurally similar to the protein tyrosine phosphatase PTP-BL. FRMPD2 is localized in a polarized fashion in epithelial cells at the basolateral membrane and partially co-localizes with the tight-junction marker protein Zonula-occuldens-1. Suppression of FRMPD2 expression via RNAi in Caco-2 cells results in an impairment of tight junction formation, indicating that FRMPD2 plays a major role in tight junction formation. Other experiments indicate that FRMPD2 is a binding partner to several catenin family members and recruitment of FRMPD2 to cell-cell contacts is dependent on E-cadherin-mediated cell-cell adhesion.
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基因ID
- 143162
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NCBI登录号
- NP_001018081
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UniProt
- Q68DX3
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途径
- Cell-Cell Junction Organization
抗原
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