FRMPD1 抗体 (C-Term)
FRMPD1
适用: 人
WB, ELISA, IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all FRMPD1 抗体
- FRMPD1 (FERM and PDZ Domain Containing 1 (FRMPD1))
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抗原表位
- AA 1330-1380, C-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FRMPD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 纯化方法
- FRMPD1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- FRMPD1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human FRMPD1. The immunogen is located within amino acids 1330 - 1380 of FRMPD1.
- 亚型
- IgG
- Top Product
- Discover our top product FRMPD1 Primary Antibody
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anti-FERM and PDZ Domain Containing 1 (FRMPD1) (AA 1-1578) antibody
FRMPD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FERM and PDZ Domain Containing 1 (FRMPD1) (C-Term) antibodyFRMPD1 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FRMPD1 antibody can be used for detection of FRMPD1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunoflourescence starting at 20 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- FRMPD1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- FRMPD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- FRMPD1 (FERM and PDZ Domain Containing 1 (FRMPD1))
- 别名
- FRMPD1 (FRMPD1 产品)
- 别名
- FRMD2 antibody, BC031840 antibody, mKIAA0967 antibody, FERM and PDZ domain containing 1 antibody, FRMPD1 antibody, Frmpd1 antibody
- 背景
- FRMPD1 Antibody: The FERM and PDZ domain containing (FRMPD) protein family consists of four proteins that contain a FERM (Four-point-one, erzin, radixin, moesin) domain and at least one PDZ (PSD-95/Discs large/Zonula-occuldens-1) domain. FRMPD1 was initially identified through a yeast two-hybrid screening with Activator of G-protein signaling 3 (AGS3), a protein that acts to stabilize the GDP-bound conformation of Gai, as the bait. FRMPD1 binds to the tetratricopeptide repeat of AGS3 and stabilizes AGS3 in a membrane environment. Suppression of FRMPD1 in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by ~50 % and enhanced the inhibition of forskolin-induced increases in cAMP. Co-immunoprecipitation studies indicate that the interaction of AGS3 with FRMPD1 is mutually exclusive with the interaction of AGS3 with Gai3, suggesting that FRMPD1 may position AGS3 in the membrane where it can then interact with Galphai.
- 基因ID
- 22844
- NCBI登录号
- NP_055722
- UniProt
- Q5SYB0
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