ANKRD27 抗体 (AA 640-690)
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北京 101111
Quick Overview for ANKRD27 抗体 (AA 640-690) (ABIN6991210)
抗原
See all ANKRD27 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 640-690
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纯化方法
- VARP Antibody is affinity chromatography purified via peptide column.
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免疫原
- VARP antibody was raised against a 15 amino acid synthetic peptide near the center of human VARP. The immunogen is located within amino acids 640 - 690 of VARP.
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亚型
- IgG
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应用备注
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VARP antibody can be used for detection of VARP by Immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- VARP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- VARP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ANKRD27 (Ankyrin Repeat Domain 27 (VPS9 Domain) (ANKRD27))
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别名
- VARP
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背景
- VARP Antibody: The VPS9 ankyrin repeat protein (VARP) binds to the Rab21, a guanine nucleotide exchange factor that plays an essential role in endocytic trafficking. VARP localizes to early endosomes and is thought to regulate endosome dynamics. VARP also interacts with TI-VAMP/VAMP7, a vesicular SNARE that mediates an exocytic pathway that is crucial to neurite growth. Depletion of VARP by RNA interference impairs neurite growth, suggesting that VARP is a positive regulator of neurite growth.
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基因ID
- 84079
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NCBI登录号
- NP_115515
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UniProt
- Q96NW4
抗原
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