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GOLPH3 抗体 (N-Term)

GOLPH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991206
发货至: 中国
  • 抗原 See all GOLPH3 抗体
    GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 44
    • 13
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 39
    • 4
    • 1
    克隆类型
    • 42
    • 2
    多克隆
    标记
    • 26
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    This GOLPH3 antibody is un-conjugated
    应用范围
    • 39
    • 13
    • 13
    • 12
    • 10
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    纯化方法
    GOLPH3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    GOLPH3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human GOLPH3. The immunogen is located within the first 50 amino acids of GOLPH3.
    亚型
    IgG
    Top Product
    Discover our top product GOLPH3 Primary Antibody
  • 应用备注
    GOLPH3 antibody can be used for detection of GOLPH3 by Western blot at 0.5 - 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    GOLPH3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    GOLPH3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))
    别名
    GOLPH3 (GOLPH3 产品)
    别名
    wu:fj66a10 antibody, zgc:101573 antibody, zgc:110223 antibody, 4733401N08Rik antibody, 5730410D03Rik antibody, AW413496 antibody, GOPP1 antibody, GPP34 antibody, MIDAS antibody, Gmx33 antibody, golgi phosphoprotein 3 antibody, golph3 antibody, CpipJ_CPIJ009278 antibody, Golph3 antibody, GOLPH3 antibody
    背景
    GOLPH3 Antibody: GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.
    基因ID
    64083
    UniProt
    Q9H4A6
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