GOLPH3 抗体 (N-Term)
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北京 101111
Quick Overview for GOLPH3 抗体 (N-Term) (ABIN6991206)
抗原
See all GOLPH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- GOLPH3 Antibody is affinity chromatography purified via peptide column.
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免疫原
- GOLPH3 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human GOLPH3. The immunogen is located within the first 50 amino acids of GOLPH3.
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亚型
- IgG
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anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 16-150) antibody
GOLPH3 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (C-Term) antibodyGOLPH3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyKD Validated GOLPH3 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB7340 unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 251-279), (C-Term) antibodyGOLPH3 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18063 unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 1-30), (N-Term) antibodyGOLPH3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18062 unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (AA 1-298) antibodyGOLPH3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) (Internal Region) antibodyVerified GOLPH3 适用: 人, 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyGOLPH3 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyGOLPH3 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3) antibodyGOLPH3 适用: 人 WB 宿主: 小鼠 Monoclonal 9A1 unconjugated
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应用备注
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GOLPH3 antibody can be used for detection of GOLPH3 by Western blot at 0.5 - 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- GOLPH3 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- GOLPH3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- GOLPH3 (Golgi phosphoprotein 3 (Coat-Protein) (GOLPH3))
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别名
- GOLPH3
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背景
- GOLPH3 Antibody: GOLPH3 was initially identified as a peripheral membrane protein localized to the trans-Golgi network, but others reported it to be primarily a mitochondrial protein that regulated the mitochondrial mass through the regulation of the mitochondria-specific phospholipid cardiolipin. GOLPH3 has since been implicated in the target of rapamycin (TOR) signalling pathway. Its overexpression in transfected cells led to and increase in anchorage-independent growth and cell proliferation in vitro. Furthermore, GOLPH3-transfected cells enhanced S6 Kinase activity in response to growth factor stimulation by EGF. Simultaneously, AKT phosphorylation increased in these cells, while these events were abrogated in GOLPH3 siRNA treated cells compared to control cells, indicating the GOLPH3 can enhance signalling through TOR-associated complexes. These results suggest that GOLPH3 is a bona fide oncogene and may be a useful target for therapeutic strategies.
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基因ID
- 64083
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UniProt
- Q9H4A6
抗原
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