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Gastrin 抗体 (C-Term)

This anti-Gastrin antibody is a 兔 多克隆 antibody detecting Gastrin in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6991203
发货至: 中国

Quick Overview for Gastrin 抗体 (C-Term) (ABIN6991203)

抗原

See all Gastrin (GAST) 抗体
Gastrin (GAST)

适用

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人, 小鼠

宿主

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  • 70
  • 2

克隆类型

  • 79
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多克隆

标记

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This Gastrin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    纯化方法

    GAS Antibody is affinity chromatography purified via peptide column.

    免疫原

    GAS antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human GAS. The immunogen is located within the last 50 amino acids of GAS.

    亚型

    IgG
  • 应用备注

    GAS antibody can be used for detection of GAS by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    GAS Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    GAS antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Gastrin (GAST)

    别名

    GAS

    背景

    GAS Antibody: Steroid receptor co-activators (SRCs) were initially described as nuclear receptor transcription co-activators, but they have recently been determined to co-regulate transcription initiated by other transcription factors. GAS is a recently identified glutamate-rich protein that interacts with SRC1, but not GRIP1 or AIB1, the other two members of the SRC family. GAS can also interact with the alpha subunit of the estrogen receptor (ERalpha), but not other receptors such as the retinoic acid receptor a, suggesting the interaction between GAS and ERalpha is relatively specific. Depletion of GAS by RNA interference in MCF7 cells led to a decrease in the mRNA and protein levels of ER target genes such as pS2, c-Myc and cyclin D1, indicating the role of GAS in the regulation of ER target genes. GAS has also been found to associate with an SET1-like methyltransferase complex specific for H3K4 methylation, suggesting that GAS has multiple roles in transcriptional regulation.

    基因ID

    79447

    NCBI登录号

    NP_078792

    UniProt

    Q9BTK6
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