PLEKHO1 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for PLEKHO1 抗体 (C-Term) (ABIN6991202)
抗原
See all PLEKHO1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- CKIP1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- CKIP1 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human CKIP1. The immunogen is located within the last 50 amino acids of CKIP1.
-
亚型
- IgG
-
-
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) antibody
PLEKHO1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 51-170) antibodyPLEKHO1 适用: 人, 小鼠 ELISA, WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 49-77), (N-Term) antibodyPLEKHO1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB19797 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 143-404) antibodyPLEKHO1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D5 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-409) antibodyPLEKHO1 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (AA 1-410) antibodyPLEKHO1 适用: 人 ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1C7 unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1) (N-Term) antibodyPLEKHO1 适用: 人, 大鼠, Cow, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
CKIP1 antibody can be used for detection of CKIP1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- CKIP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- CKIP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))
-
别名
- CKIP1
-
背景
- CKIP1 Antibody: CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha', and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.
-
基因ID
- 51177
-
NCBI登录号
- NP_057358
-
UniProt
- Q53GL0
抗原
-
