CENPO 抗体 (AA 170-220)
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北京 101111
Quick Overview for CENPO 抗体 (AA 170-220) (ABIN6991201)
抗原
See all CENPO 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-220
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纯化方法
- CENPO Antibody is affinity chromatography purified via peptide column.
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免疫原
- CENPO antibody was raised against a 16 amino acid synthetic peptide from near the center of human CENPO. The immunogen is located within amino acids 170 - 220 of CENPO.
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亚型
- IgG
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应用备注
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CENPO antibody can be used for detection of CENPO by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CENPO Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CENPO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CENPO (Centromere Protein O (CENPO))
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别名
- CENPO
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背景
- CENPO Antibody: Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.
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基因ID
- 79172
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NCBI登录号
- NP_077298
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UniProt
- Q9BU64
抗原
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