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CENPO 抗体 (AA 170-220)

This anti-CENPO antibody is a 兔 多克隆 antibody detecting CENPO in ELISA 和 WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6991201
发货至: 中国
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Quick Overview for CENPO 抗体 (AA 170-220) (ABIN6991201)

抗原

See all CENPO 抗体
CENPO (Centromere Protein O (CENPO))

适用

人, 小鼠, 大鼠

宿主

  • 22

克隆类型

  • 22
多克隆

标记

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CENPO antibody is un-conjugated

应用范围

  • 15
  • 10
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB)
  • 抗原表位

    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 170-220

    纯化方法

    CENPO Antibody is affinity chromatography purified via peptide column.

    免疫原

    CENPO antibody was raised against a 16 amino acid synthetic peptide from near the center of human CENPO. The immunogen is located within amino acids 170 - 220 of CENPO.

    亚型

    IgG
  • 应用备注

    CENPO antibody can be used for detection of CENPO by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    CENPO Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    CENPO antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    CENPO (Centromere Protein O (CENPO))

    别名

    CENPO

    背景

    CENPO Antibody: Accurate chromosome segregation during mitosis requires a kinetochore to assemble correctly at the centromere of each chromatid and form a dynamic interface with the microtubules of the mitotic spindle. The kinetochore assembly includes the multisubunit CENP-H/I complex which can be divided into three functional classes based on phenotype analysis. One of these classes is referred to as the CENP-O class of proteins of which CENPO is the exemplar. These proteins form a stable complex with each other and are required for proper kinetochore function and for recovery from mitotic spindle damage. CENPO has also been shown to be an auto-antigen in a small population of anti-centromere antibodies- (ACA-) positive patients with sclerodoma.

    基因ID

    79172

    NCBI登录号

    NP_077298

    UniProt

    Q9BU64
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