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INSM1 抗体 (N-Term)

The 兔 多克隆 anti-INSM1 antibody (ABIN6991197) specifically detects INSM1 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6991197
发货至: 中国
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Quick Overview for INSM1 抗体 (N-Term) (ABIN6991197)

抗原

See all INSM1 抗体
INSM1 (Insulinoma-Associated 1 (INSM1))

适用

  • 18
  • 15
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 19

克隆类型

  • 16
  • 3
多克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This INSM1 antibody is un-conjugated

应用范围

  • 9
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 90-140, N-Term

    纯化方法

    IA-1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    IA-1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human IA-1. The immunogen is located within amino acids 90 - 140 of IA-1.

    亚型

    IgG
  • 应用备注

    IA-1 antibody can be used for detection of IA-1 by Western blot at 1 μ,g/mL.

    Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IA-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IA-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    INSM1 (Insulinoma-Associated 1 (INSM1))

    别名

    IA-1

    背景

    IA-1 Antibody: IA-1, also known as INSM1, is an essential five zinc-finger transcription factor that while initially identified from an insulinoma cDNA library, is expressed in the developing nervous system. Specifically, IA-1 is expressed as early as E9.5 in mice in the fore-, mid- and hindbrain, spinal cord, retina, and olfactory bulb. It is thought that IA-1 functions as a transcriptional repressor, and is a part of several signaling pathways including those of Notch and sonic hedgehog in addition to that of Ngn3 during pancreatic endocrine cell differentiation. IA-1 is also expressed in multiple tumors, including the majority of neuroendocrine tumors tested so far as well as nearly 100 % of all small cell lung carcinomas, indicating that IA-1 may be an important target in cancer therapy.

    基因ID

    3642

    NCBI登录号

    NP_002187

    UniProt

    Q01101
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