RUSC2 抗体 (C-Term)
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Quick Overview for RUSC2 抗体 (C-Term) (ABIN6991196)
抗原
See all RUSC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1410-1460, C-Term
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特异性
- At least three isoforms are known to exist, this antibody will only detect the longest isoform. This antibody is predicted to not cross-react with RUSC1.
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纯化方法
- RUSC2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RUSC2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RUSC2. The immunogen is located within amino acids 1410 - 1460 of RUSC2.
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亚型
- IgG
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应用备注
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RUSC2 antibody can be used for detection of RUSC2 by immunohistrochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RUSC2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RUSC2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RUSC2 (RUN and SH3 Domain Containing 2 (RUSC2))
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别名
- RUSC2
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背景
- RUSC2 Antibody: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30 % amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.
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基因ID
- 9853
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NCBI登录号
- NP_001098673
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UniProt
- Q8N2Y8
抗原
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