JMJD6 抗体 (N-Term)
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北京 101111
Quick Overview for JMJD6 抗体 (N-Term) (ABIN6991182)
抗原
See all JMJD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120, N-Term
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纯化方法
- JMJD6 Antibody is affinity chromatography purified via peptide column.
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免疫原
- JMJD6 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human JMJD6. The immunogen is located within amino acids 70 - 120 of JMJD6.
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亚型
- IgG
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应用备注
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JMJD6 antibody can be used for detection of JMJD6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- JMJD6 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- JMJD6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- JMJD6 (Jumonji Domain Containing 6 (JMJD6))
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别名
- JMJD6
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背景
- JMJD6 Antibody: The jumonji domain-containing protein (JMJD) family is defined by the presence of the JmjC domain that is observed in several diverse species. JMJD6 was initially identified as a membrane protein that participates in phagocytosis but recent studies have shown that it has other functions when it is expressed in the cytosol and nucleus. JMJD6 is thought to play important roles in regulation of development and differentiation as knockdown experiments in mice resulted in neonatal lethality with severe defects in the morphology of numerous organs. JMJD6 also can catalyze the lysyl-hydroxylation of U2AF65, a protein involved with RNA splicing, suggesting that some of the functions attributed to JMJD6 may be due to its regulatory activity of RNA splicing.
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基因ID
- 23210
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UniProt
- Q6NYC1
抗原
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