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KDM3B 抗体 (AA 1050-1100)

KDM3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991177
发货至: 中国
  • 抗原 See all KDM3B 抗体
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    抗原表位
    • 15
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    AA 1050-1100
    适用
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    人, 小鼠, 大鼠
    宿主
    • 60
    • 1
    克隆类型
    • 61
    多克隆
    标记
    • 31
    • 3
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    This KDM3B antibody is un-conjugated
    应用范围
    • 47
    • 21
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    • 7
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    • 4
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    特异性
    This antibody will not cross-react with JMJD1A or JMJD1C.
    纯化方法
    JMJD1B Antibody is affinity chromatography purified via peptide column.
    免疫原
    JMJD1B antibody was raised against a 20 amino acid synthetic peptide from near the center of human JMJD1B. The immunogen is located within amino acids 1050 - 1100 of JMJD1B.
    亚型
    IgG
    Top Product
    Discover our top product KDM3B Primary Antibody
  • 应用备注
    JMJD1B antibody can be used for detection of JMJD1B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    JMJD1B Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    JMJD1B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    别名
    JMJD1B (KDM3B 产品)
    背景
    JMJD1B Antibody: The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung cancers indicating that the role of JMJD1B in cancer formation and progression is more complex than originally postulated. At least three isoforms of JMJD1B are known to exist.
    基因ID
    51780
    UniProt
    Q7LBC6
    途径
    Warburg Effect
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