IRGC 抗体 (C-Term)
Quick Overview for IRGC 抗体 (C-Term) (ABIN6991167)
抗原
See all IRGC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Two isoforms of IRGC are known to exist, this antibody will recognize both isoforms.
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纯化方法
- IRGC Antibody is affinity chromatography purified via peptide column.
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免疫原
- IRGC antibody was raised against a 12 amino acid synthetic peptide near the carboxy terminus of human IRGC. The immunogen is located within the last 50 amino acids of IRGC.
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亚型
- IgG
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anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibody
IRGC 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (AA 73-122) antibodyIRGC 适用: 人, 大鼠, 小鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Immunity-Related GTPase Family, Cinema (IRGC) (C-Term) antibodyIRGC 适用: 人, 大鼠, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IRGC antibody can be used for detection of IRGC by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IRGC Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IRGC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
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别名
- IRGC
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背景
- IRGC Antibody: Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
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基因ID
- 56269
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NCBI登录号
- NP_062558
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UniProt
- Q6NXR0
抗原
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