SYPL2 抗体 (C-Term)
The 兔 多克隆 anti-SYPL2 antibody is suitable to detect SYPL2 in samples from 人, 小鼠 和 大鼠. It has been validated for ELISA, WB, IHC (p) 和 IF.
产品编号 ABIN6991151
发货至:
中国
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Quick Overview for SYPL2 抗体 (C-Term) (ABIN6991151)
抗原
See all SYPL2 抗体
SYPL2
(Synaptophysin-Like 2 (SYPL2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SYPL2 antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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抗原表位
- C-Term
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特异性
- At least two isoforms of SYPL2 are known to exist. SYPL2 antibody will not cross-react with SYPL1.
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纯化方法
- SYPL2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- SYPL2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human SYPL. The immunogen is located within the last 50 amino acids of SYPL2.
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亚型
- IgG
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anti-Synaptophysin-Like 2 (SYPL2) (C-Term) antibody
SYPL2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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SYPL2 antibody can be used for detection of SYPL2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- SYPL2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- SYPL2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SYPL2 (Synaptophysin-Like 2 (SYPL2))
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别名
- SYPL2
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背景
- SYPL2 Antibody: SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores.
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基因ID
- 284612
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NCBI登录号
- NP_001035799
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UniProt
- Q5VXT5
抗原
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