PPPDE1 抗体 (C-Term)
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北京 101111
Quick Overview for PPPDE1 抗体 (C-Term) (ABIN6991134)
抗原
See all PPPDE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- PNAS4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PNAS4 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human PNAS4. The immunogen is located within the last 50 amino acids of PNAS4.
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亚型
- IgG
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anti-PPPDE Peptidase Domain Containing 1 (PPPDE1) (Internal Region) antibody
Verified PPPDE1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-PPPDE Peptidase Domain Containing 1 (PPPDE1) (C-Term) antibodyPPPDE1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-PPPDE Peptidase Domain Containing 1 (PPPDE1) (C-Term) antibodyPPPDE1 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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PNAS4 antibody can be used for detection of PNAS4 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PNAS4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PNAS4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PPPDE1 (PPPDE Peptidase Domain Containing 1 (PPPDE1))
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别名
- PNAS4
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背景
- PNAS4 Antibody: PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.
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基因ID
- 51029
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NCBI登录号
- NP_057160
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UniProt
- Q9BSY9
抗原
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