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FBLN3 抗体 (C-Term)

This anti-FBLN3 antibody is a 兔 多克隆 antibody detecting FBLN3 in WB, ELISA, ICC 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6991132
发货至: 中国
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Quick Overview for FBLN3 抗体 (C-Term) (ABIN6991132)

抗原

See all FBLN3 抗体
FBLN3 (Fibulin 3 (FBLN3))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This FBLN3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    AA 410-460, C-Term

    特异性

    At least three isoforms of Fibulin 3 are known to exist. This antibody is predicted to not cross-react with other Fibulin proteins.

    纯化方法

    Fibulin 3 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Fibulin 3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human Fibulin 3. The immunogen is located within amino acids 410 - 460 of Fibulin 3.

    亚型

    IgG
  • 应用备注

    Fibulin 3 antibody can be used for detection of Fibulin 3 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Fibulin 3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Fibulin 3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    FBLN3 (Fibulin 3 (FBLN3))

    别名

    Fibulin 3

    背景

    Fibulin 3 Antibody: Fibulin 3, also known as epidermal growth factor (EGF)-containing fibulin-like extracellular matrix protein 1 (EFEMP1), is a member of the fibulin family of extracellular glycoproteins, a group of proteins that are widely distributed and frequently associated with vascular and elastic tissues. The fibulin proteins typically contain a tandem array of EGF-like repeats and a fibulin-type COOH-terminal module. Aberrant accumulation of Fibulin 3 in the endoplasmic reticulum of retinal pigment epithelial cells has been shown to be associated with inherited forms of macular degeneration, but the loss of Fibulin 3 expression does not lead to macular degeneration but rather the appearance of hernias due to a reduction of elastic fibers of fascial connective tissue. Recent experiments have shown that expression of Fibulin 3 promotes tumor growth and may thus be a therapeutic target.

    分子量

    Predicted: 52 kDa

    Observed: 47 kDa

    基因ID

    2202

    NCBI登录号

    NP_001034437

    UniProt

    Q12805

    途径

    EGFR Signaling Pathway
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