RGS21 抗体 (AA 40-90)
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北京 101111
Quick Overview for RGS21 抗体 (AA 40-90) (ABIN6991130)
抗原
See all RGS21 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-90
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纯化方法
- RGS21 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RGS21 antibody was raised against a 16 amino acid synthetic peptide near the center of human RGS21. The immunogen is located within amino acids 40 - 90 of RGS21.
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亚型
- IgG
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应用备注
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RGS21 antibody can be used for detection of RGS21 by Western blot at 0.5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RGS21 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RGS21 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RGS21 (Regulator of G-Protein Signaling 21 (RGS21))
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别名
- RGS21
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背景
- RGS21 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes.
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基因ID
- 431704
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NCBI登录号
- NP_001034241
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UniProt
- Q2M5E4
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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