ST3GAL6 抗体 (C-Term)
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Quick Overview for ST3GAL6 抗体 (C-Term) (ABIN6991119)
抗原
See all ST3GAL6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-280, C-Term
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纯化方法
- ST3gal6 Antibody is affinity chromatography purified via peptide column.
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免疫原
- ST3gal6 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ST3gal6. The immunogen is located within amino acids 230 - 280 of ST3gal6.
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亚型
- IgG
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应用备注
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ST3gal6 antibody can be used for detection of ST3gal6 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- ST3gal6 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- ST3gal6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- ST3GAL6 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 6 (ST3GAL6))
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别名
- ST3gal6
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背景
- ST3gal6 Antibody: Sialyltransferases catalyze the transfer of sialic acid from cytidine 5-prime monophospho-N-acetylneuraminic acid (CMP-NeuAc) to terminal positions of glycoprotein and glycolipid carbohydrate groups. Terminal NeuAc residues are key determinants of carbohydrate structures, such as the sialyl-Lewis X determinants, and are widely distributed in many cell types. However, cancer cells often express more heavily sialylated glycans on their cell surface and this feature sometimes correlates with invasiveness. In contrast, expression of ST3gal6, a member of the sialyltransferase family that sialylates type II lactosamine structures on glycoproteins and glycolipids, was found to be significantly decreased by hypermethylation of the gene in gastrointestinal cancer. At least three isoforms of ST3gal6 are known to exist.
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基因ID
- 10402
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NCBI登录号
- NP_006091
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UniProt
- Q9Y274
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途径
- Glycosaminoglycan Metabolic Process
抗原
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