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SIGLEC11 抗体 (C-Term)

SIGLEC11 适用: 人 ELISA, WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991110
发货至: 中国
  • 抗原 See all SIGLEC11 抗体
    SIGLEC11 (Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11))
    抗原表位
    • 15
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    C-Term
    适用
    宿主
    • 28
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    克隆类型
    • 29
    • 1
    多克隆
    标记
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    • 1
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    This SIGLEC11 antibody is un-conjugated
    应用范围
    • 17
    • 15
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    • 4
    • 3
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    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    纯化方法
    Siglec11 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Siglec11 antibody was raised against an 18 amino acid synthetic peptide from near the carboxy terminus of human Siglec11. The immunogen is located within the last 50 amino acids of Siglec11.
    亚型
    IgG
    Top Product
    Discover our top product SIGLEC11 Primary Antibody
  • 应用备注
    Siglec11 antibody can be used for detection of Siglec11 by Western blot at 1 μ,g/mL. Despite its predicted size, Siglec11 migrates at a higher than expected molecular weight in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Siglec11 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Siglec11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SIGLEC11 (Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11))
    别名
    Siglec11 (SIGLEC11 产品)
    别名
    sialic acid binding Ig like lectin 11 antibody, SIGLEC11 antibody
    背景
    Siglec11 Antibody: Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system. Siglec11 is unlike other siglecs in that it binds specifically to alpha2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues. Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain, suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene. Following treatment of Siglec11-transfected cells with pervanadate, Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2. At least five isoforms of Siglec11 are known to exist. Siglec11 antibody will not cross-react with Siglec10.
    基因ID
    114132
    NCBI登录号
    NP_443116
    UniProt
    Q96RL6
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