RUNX1 抗体 (AA 160-210)
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北京 101111
Quick Overview for RUNX1 抗体 (AA 160-210) (ABIN6991109)
抗原
See all RUNX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-210
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纯化方法
- RUNX1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RUNX1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RUNX1. The immunogen is located within amino acids 160 - 210 of RUNX1.
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亚型
- IgG
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应用备注
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RUNX1 antibody can be used for detection of RUNX1 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RUNX1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RUNX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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别名
- RUNX1
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背景
- RUNX1 Antibody: RUNX1 is one of three mammalian RUNX genes that control multiple aspects of embryonic development and are responsible for the pathogenesis of many human diseases. RUNX1 plays major roles in the development of nociceptive sensory neurons in addition to hematopoietic stem cells (HSC) with the exception of the erythroid lineage. During development, Notch signals mediate RUNX1 induction with SCL/GATA/Ets factors, and Wnt signals potentially cooperate with RUNX1 to facilitate adult HSC expansion via cooperative induction of cyclin D, cdk4, and other cell cycle regulators. In turn, RUNX1 regulates cell cycle transitions dependent on functional/physical interactions with other proteins such as HDAC1 and -3, mSin3A, p300, SMAD proteins, and LEF/TCF.
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基因ID
- 861
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UniProt
- Q01196
抗原
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