MATN1 抗体 (C-Term)
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北京 101111
Quick Overview for MATN1 抗体 (C-Term) (ABIN6991098)
抗原
See all MATN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 370-420, C-Term
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纯化方法
- MATN1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- MATN1 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human MATN1. The immunogen is located within amino acids 370 - 420 of MATN1.
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亚型
- IgG
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应用备注
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MATN1 antibody can be used for detection of MATN1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MATN1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MATN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MATN1 (Matrilin 1, Cartilage Matrix Protein (MATN1))
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别名
- MATN1
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背景
- MATN1 Antibody: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.
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基因ID
- 4146
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NCBI登录号
- NP_002370
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UniProt
- P21941
抗原
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