RCAN2 抗体 (AA 70-120)
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北京 101111
Quick Overview for RCAN2 抗体 (AA 70-120) (ABIN6991070)
抗原
See all RCAN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120
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纯化方法
- RCAN2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- RCAN2 antibody was raised against a 14 amino acid synthetic peptide near the center of human RCAN2. The immunogen is located within amino acids 70 - 120 of RCAN2.
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亚型
- IgG
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anti-Regulator of Calcineurin 2 (RCAN2) (AA 6-37), (N-Term) antibody
RCAN2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB02309 unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (AA 88-197) antibodyRCAN2 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (AA 1-225) antibodyRCAN2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (AA 71-120) antibodyRCAN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (Middle Region) antibodyRCAN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Regulator of Calcineurin 2 (RCAN2) (Center) antibodyRCAN2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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RCAN2 antibody can be used for detection of RCAN2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- RCAN2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- RCAN2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- RCAN2 (Regulator of Calcineurin 2 (RCAN2))
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别名
- RCAN2
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背景
- RCAN2 Antibody: Regulator of calcineurin 2 (RCAN2), also known as ZAKI4 and DSCR1L1, is expressed as two isoforms differing at their N-terminus. The longer of the two (isoform 1) is expressed exclusively in the brain, while isoform 2 is ubiquitously expressed, with highest expression in brain, heart, and muscle. Both isoforms bind to the catalytic subunit of calcineurin, a Ca++-dependent protein phosphatase involved in several neuronal functions, though their C-terminal region and inhibit calcineurin's activity. Unlike isoform 1 of RCAN2, the expression of the second isoform is not induced by the thyroid hormone T3. RCAN2 is a member of a family of three endogenous calcineurin regulators that are located near the minimal supernumerary fragment of chromosome 21 in individuals with Down syndrome, suggesting that they play a role in this syndrome. Multiple isoforms of RCAN2 are known to exist.
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基因ID
- 53901
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UniProt
- Q9JHG2
抗原
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