FNIP2 抗体 (C-Term)
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北京 101111
Quick Overview for FNIP2 抗体 (C-Term) (ABIN6991067)
抗原
See all FNIP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 860-910, C-Term
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特异性
- Multiple isoforms of FNIP2 are known to exist. This antibody is predicted to not cross-react with FNIP1.
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纯化方法
- FNIP2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- FNIP2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human FNIP2. The immunogen is located within amino acids 860 - 910 of FNIP2.
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亚型
- IgG
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应用备注
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FNIP2 antibody can be used for detection of FNIP2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- FNIP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- FNIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FNIP2 (Folliculin Interacting Protein 2 (FNIP2))
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别名
- FNIP2
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背景
- FNIP2 Antibody: FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin is thought to act as a tumor suppressor as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, a protein that shares 49 % identity to FNIP2, bind to AMPK, an important energy sensor in cells that negatively regulates the mammalian target of rapamycin (mTOR), a protein that is thought to be the master switch for cell growth and proliferation. FNIP1 and FNIP2 are able to form homo- and heteromeric multimers, suggesting these proteins may have a functional relationship.
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基因ID
- 57600
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NCBI登录号
- NP_065891
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UniProt
- Q9P278
抗原
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