PDCD5 抗体 (C-Term)
Quick Overview for PDCD5 抗体 (C-Term) (ABIN6991058)
抗原
See all PDCD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- PDCD5 Antibody is affinity chromatography purified via peptide column.
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免疫原
- PDCD5 antibody was raised against a 21 amino acid synthetic peptide from near the carboxy terminus of human PDCD5. The immunogen is located within the last 50 amino acids of PDCD5.
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亚型
- IgG
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anti-Programmed Cell Death 5 (PDCD5) (C-Term) antibody
PDCD5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 1-125) antibodyPDCD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 1-125) antibodyPDCD5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 2-125) antibodyPDCD5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) antibodyPDCD5 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (AA 1-125) antibodyPDCD5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) antibodyPDCD5 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (N-Term) antibodyPDCD5 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 5 (PDCD5) (C-Term) antibodyPDCD5 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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PDCD5 antibody can be used for detection of PDCD5 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PDCD5 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- PDCD5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- PDCD5 (Programmed Cell Death 5 (PDCD5))
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别名
- PDCD5
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背景
- PDCD5 Antibody: Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis. The nucleotide polymorphisms in the 5'-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.
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基因ID
- 9141
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UniProt
- O14737
抗原
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