IL16 抗体 (N-Term)
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北京 101111
Quick Overview for IL16 抗体 (N-Term) (ABIN6991050)
抗原
See all IL16 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 140-190, N-Term
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特异性
- This antibody will only detect the NIL-16 isoform.
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纯化方法
- IL-16 Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-16 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human IL-16. The immunogen is located within amino acids 140 - 190 of IL-16.
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亚型
- IgG
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anti-Interleukin 16 (IL16) (AA 1203-1332) antibody
IL16 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) (AA 1203-1322) antibodyIL16 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) (C-Term) antibodyIL16 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) (C-Term) antibodyIL16 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) (AA 1-454) antibodyIL16 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) antibodyIL16 适用: 人 IHC, IHC (p) 宿主: 小鼠 Monoclonal G11-II unconjugated
anti-Interleukin 16 (IL16) antibody (Biotin)IL16 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 16 (IL16) (AA 1212-1332) antibodyIL16 适用: 人 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) antibodyIL16 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 16 (IL16) (C-Term) antibodyIL16 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IL-16 antibody can be used for detection of IL-16 by Western blot at 2.5 - 5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-16 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-16 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL16 (Interleukin 16 (IL16))
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别名
- IL-16
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背景
- IL-16 Antibody: IL-16 was initially identified as a chemotactic cytokine, but is now known to possess a wide range of activities. Later studies have more fully characterized IL-16 as an immunomodulatory cytokine that contributes to the regulatory process of CD4+ T cell recruitment and activation at sites of inflammation in association with asthma and several autoimmune diseases. The precursor of IL-16 (pro-IL-16) is thought to be cleaved towards the C-terminal region by Caspase-3, releasing a 20 kDa active form that binds to and signals through CD4. Besides acting as a chemotactic cytokine, IL-16 is thought to also be involved in the regulation of T cell proliferation and multiple infectious, immune-mediated, and autoimmune inflammatory disorders including irritable bowel syndrome, systemic lupus erythematosus, and neurodegenerative disorders. At least two isoforms of IL-16 are known to exist, the longer isoform (also known as NIL-16) is detected only in neurons of the cerebellum and hippocampus.
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分子量
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Predicted: 145 kDa
Observed: 160 kDa -
基因ID
- 3603
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UniProt
- Q14005
抗原
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