TREX2 抗体 (C-Term)
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- 抗原 See all TREX2 (Trex2) 抗体
- TREX2 (Trex2) (three Prime Repair Exonuclease 2 (Trex2))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TREX2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- This TREX2 antibody will not cross-react with the related protein TREX1.
- 纯化方法
- TREX2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TREX2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human TREX2. The immunogen is located within the last 50 amino acids of TREX2.
- 亚型
- IgG
- Top Product
- Discover our top product Trex2 Primary Antibody
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anti-three Prime Repair Exonuclease 2 (Trex2) (AA 156-189), (C-Term) antibody
Trex2 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51322 unconjugated
anti-three Prime Repair Exonuclease 2 (Trex2) (AA 264-299), (C-Term) antibodyTrex2 适用: 人 WB 宿主: 兔 Polyclonal RB51418 unconjugated
anti-three Prime Repair Exonuclease 2 (Trex2) (AA 223-276), (C-Term) antibodyTrex2 适用: 大鼠 WB 宿主: 兔 Polyclonal RB51156 unconjugated
anti-three Prime Repair Exonuclease 2 (Trex2) (Internal Region) antibodyVerified Trex2 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-three Prime Repair Exonuclease 2 (Trex2) (C-Term) antibodyTrex2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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TREX2 antibody can be used for detection of TREX2 by Western blot at 2.5 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TREX2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TREX2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- TREX2 (Trex2) (three Prime Repair Exonuclease 2 (Trex2))
- 别名
- TREX2 (Trex2 产品)
- 别名
- RGD1562245 antibody, three prime repair exonuclease 2 antibody, TREX2 antibody, Trex2 antibody
- 背景
- TREX2 Antibody: TREX2 is one of two major human 3' to 5' exonucleases which are required for checkpoint signaling after DNA damage. While the related protein TREX1 is required for ATR expression and mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis, less is known about TREX2. Like TREX1, TREX2 is ubiquitously expressed in all tissues examined. X-ray crystallography studies of TREX2-single strand DNA complexes revealed that TREX2 binds DNA as a dimer and may act to displace the second DNA strand, suggesting that TREX2 unzips and denatures double stranded DNA and feed the substrate DNA strand into the TREX2 active site. At least two isoforms of TREX2 are known to exist.
- 基因ID
- 11219
- UniProt
- Q9BQ50
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