Junctophilin 2 抗体 (C-Term)
Quick Overview for Junctophilin 2 抗体 (C-Term) (ABIN6991018)
抗原
See all Junctophilin 2 (JPH2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 510-560, C-Term
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纯化方法
- JPH2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- JPH2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human JPH2. The immunogen is located within amino acids 510 - 560 of JPH2.
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亚型
- IgG
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anti-Junctophilin 2 (JPH2) antibody
JPH2 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 2 (JPH2) (AA 66-115) antibodyJPH2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 猴, Bat, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 2 (JPH2) (AA 408-457) antibodyJPH2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Junctophilin 2 (JPH2) (N-Term) antibodyJPH2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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JPH2 antibody can be used for detection of JPH2 by Western blot at 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- JPH2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- JPH2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Junctophilin 2 (JPH2)
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别名
- JPH2
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背景
- JPH2 Antibody: Junctional complexes between the plasma membrane (PM) and endoplasmic/sarcoplasmic reticulum (ER/SR) are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. Junctophilins (JPs) are important components of the junctional complexes. JPs are composed of a carboxy-terminal hydrophobic segment spanning the ER/SR membrane and a remaining cytoplasmic domain that shows specific affinity for the PM. Four JPs have been identified as tissue-specific subtypes derived from different genes: JPH1 is expressed in skeletal muscle, JPH2 is detected throughout all muscle cell types, and JPH3 and JPH4 are predominantly expressed in the brain and contribute to the subsurface cistern formation in neurons. JPH2-null mice died of embryonic cardiac arrest and human patients with mutations in the JPH2 gene showed hypertrophic cardiomyopathy, demonstrating the importance of this protein. Multiple isoforms of JPH2 are known to exist.
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基因ID
- 84502
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NCBI登录号
- NP_065166
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UniProt
- Q96JJ6
抗原
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