IL-17 抗体 (AA 50-100)
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北京 101111
Quick Overview for IL-17 抗体 (AA 50-100) (ABIN6991012)
抗原
See all IL-17 (IL17) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 50-100
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纯化方法
- IL-17 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-IL-17 antibody was raised against a peptide corresponding to 16 amino acids near the center of mature human IL-17. The immunogen is located within amino acids 50-100 of IL-17.
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亚型
- IgG
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应用备注
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WB: 0.125-2 μ,g/mL, IF: 5-20 μ,g/mL, IHC: 1-5 μ,g/mL .
Antibody validated: Western Blot in human samples, Immunofluorescence in mouse samples, Immunohistochemistry in human and mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-17 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL-17 (IL17) (Interleukin 17 (IL17))
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别名
- IL-17
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背景
- IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κ,B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.
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分子量
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Predicted: 17.5kD
Observed: 18 kDa -
基因ID
- 3605
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NCBI登录号
- NP_002181
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UniProt
- Q16552
抗原
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