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IL-17 抗体 (AA 50-100)

This anti-IL-17 antibody is a 兔 多克隆 antibody detecting IL-17 in WB, ELISA, IHC (p) 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6991012
发货至: 中国

Quick Overview for IL-17 抗体 (AA 50-100) (ABIN6991012)

抗原

See all IL-17 (IL17) 抗体
IL-17 (IL17) (Interleukin 17 (IL17))

适用

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人, 小鼠

宿主

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  • 9
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克隆类型

  • 87
  • 62
多克隆

标记

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This IL-17 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 16
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    • 1
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    AA 50-100

    纯化方法

    IL-17 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-IL-17 antibody was raised against a peptide corresponding to 16 amino acids near the center of mature human IL-17. The immunogen is located within amino acids 50-100 of IL-17.

    亚型

    IgG
  • 应用备注

    WB: 0.125-2 μ,g/mL, IF: 5-20 μ,g/mL, IHC: 1-5 μ,g/mL .

    Antibody validated: Western Blot in human samples, Immunofluorescence in mouse samples, Immunohistochemistry in human and mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-17 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-17 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    IL-17 (IL17) (Interleukin 17 (IL17))

    别名

    IL-17

    背景

    IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κ,B and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

    分子量

    Predicted: 17.5kD

    Observed: 18 kDa

    基因ID

    3605

    NCBI登录号

    NP_002181

    UniProt

    Q16552
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