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ITGA4 抗体 (AA 220-270)

The 兔 多克隆 anti-ITGA4 antibody (ABIN6990993) specifically detects ITGA4 in WB, ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6990993
发货至: 中国
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Quick Overview for ITGA4 抗体 (AA 220-270) (ABIN6990993)

抗原

See all ITGA4 抗体
ITGA4 (Integrin alpha 4 (ITGA4))

适用

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人, 小鼠, 大鼠

宿主

  • 73
  • 66
  • 35

克隆类型

  • 120
  • 55
  • 2
多克隆

标记

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This ITGA4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 11
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    AA 220-270

    特异性

    At least two isoforms are known to exist. The immunogen to this antibody is within the Integrin alpha4 recombinant protein fragment and thus will recognize it.

    纯化方法

    Integrin alpha 4 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Integrin alpha 4 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Integrin alpha 4. The immunogen is located within amino acids 220 - 270 of Integrin alpha 4.

    亚型

    IgG
  • 应用备注

    Integrin alpha 4 antibody can be used for the detection of Integrin alpha 4 by Western blot at 1 μ,g/mL. Despite its predicted molecular weight, Integrin alpha4 will often run at higher molecular weight in SDS-PAGE. Antibody can also be used for immunoflourescence starting at 2 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Integrin alpha 4 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Integrin alpha 4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    ITGA4 (Integrin alpha 4 (ITGA4))

    别名

    Integrin alpha 4

    背景

    Integrin alpha 4 Antibody: The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

    基因ID

    3676

    NCBI登录号

    NP_000876

    UniProt

    P13612

    途径

    Integrin Complex
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