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MEX3D 抗体 (AA 360-410)

This anti-MEX3D antibody is a 兔 多克隆 antibody detecting MEX3D in WB, ELISA, IHC (p) 和 IF. Suitable for 人.
产品编号 ABIN6990992
发货至: 中国

Quick Overview for MEX3D 抗体 (AA 360-410) (ABIN6990992)

抗原

See all MEX3D 抗体
MEX3D (Mex-3 Homolog D (MEX3D))

适用

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宿主

  • 16
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克隆类型

  • 17
多克隆

标记

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This MEX3D antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 1
    • 1
    AA 360-410

    纯化方法

    Rkhd1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rkhd1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Rkhd1. The immunogen is located within amino acids 360 - 410 of Rkhd1.

    亚型

    IgG
  • 应用备注

    Rkhd1 antibody can be used for detection of Rkhd1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rkhd1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Rkhd1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    MEX3D (Mex-3 Homolog D (MEX3D))

    别名

    Rkhd1

    背景

    Rkhd1 Antibody: Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.

    基因ID

    399664

    UniProt

    Q86XN8
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