MEX3D 抗体 (AA 360-410)
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北京 101111
Quick Overview for MEX3D 抗体 (AA 360-410) (ABIN6990992)
抗原
See all MEX3D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 360-410
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纯化方法
- Rkhd1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Rkhd1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Rkhd1. The immunogen is located within amino acids 360 - 410 of Rkhd1.
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亚型
- IgG
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anti-Mex-3 Homolog D (MEX3D) antibody
MEX3D 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB8220 unconjugated
anti-Mex-3 Homolog D (MEX3D) (AA 418-488) antibodyMEX3D 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Mex-3 Homolog D (MEX3D) (Center) antibodyMEX3D 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Rkhd1 antibody can be used for detection of Rkhd1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rkhd1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Rkhd1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MEX3D (Mex-3 Homolog D (MEX3D))
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别名
- Rkhd1
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背景
- Rkhd1 Antibody: Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
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基因ID
- 399664
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UniProt
- Q86XN8
抗原
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