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SPRED1 抗体 (AA 120-170)

This anti-SPRED1 antibody is a 兔 多克隆 antibody detecting SPRED1 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990991
发货至: 中国

Quick Overview for SPRED1 抗体 (AA 120-170) (ABIN6990991)

抗原

See all SPRED1 抗体
SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

适用

人, 小鼠, 大鼠

宿主

  • 39
  • 7

克隆类型

  • 39
  • 7
多克隆

标记

  • 22
  • 6
  • 5
  • 5
  • 4
  • 4
This SPRED1 antibody is un-conjugated

应用范围

  • 41
  • 35
  • 21
  • 8
  • 6
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-170

    纯化方法

    Spred1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Spred1 antibody was raised against a 20 amino acid synthetic peptide near the center of the human Spred1. The immunogen is located within amino acids 120 - 170 of Spred1.

    亚型

    IgG
  • 应用备注

    Spred1 antibody can be used for detection of Spred1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Spred1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    Spred1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))

    别名

    Spred1

    背景

    Spred1 Antibody: The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes, it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). This Spred1 antibody is predicted to have no cross-reactivity to Spred2 or Spred3.

    基因ID

    161742

    NCBI登录号

    NP_689807

    UniProt

    Q7Z699

    途径

    Positive Regulation of Response to DNA Damage Stimulus
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