ZNF350 抗体 (C-Term)
Quick Overview for ZNF350 抗体 (C-Term) (ABIN6990987)
抗原
See all ZNF350 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 410-460, C-Term
-
纯化方法
- ZBRK1 Antibody is affinity chromatography purified via peptide column.
-
免疫原
- ZBRK1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human ZBRK1. The immunogen is located within amino acids 410 - 460 of ZBRK1.
-
亚型
- IgG
-
-
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibody
ZNF350 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibodyZNF350 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 108-157) antibodyZNF350 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 119-168) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 233-532) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ZBRK1 antibody can be used for detection of ZBRK1 by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- ZBRK1 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- ZBRK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- ZNF350 (Zinc Finger Protein 350 (ZNF350))
-
别名
- ZBRK1
-
背景
- ZBRK1 Antibody: ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator with tumor suppressor activity. ZBRK1 binds to a specific sequence within the GADD45 gene, supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription. Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD), and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements. These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions.
-
基因ID
- 59348
-
NCBI登录号
- NP_067645
-
UniProt
- Q9GZX5
抗原
-
