CNOT4 抗体 (N-Term)
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北京 101111
Quick Overview for CNOT4 抗体 (N-Term) (ABIN6990985)
抗原
See all CNOT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-120, N-Term
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纯化方法
- CNOT4 Antibody is affinity chromatography purified via peptide column.
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免疫原
- CNOT4 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of the human CNOT4. The immunogen is located within amino acids 70 - 120 of CNOT4.
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亚型
- IgG
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anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) (AA 190-455) antibody
CNOT4 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) (N-Term) antibodyCNOT4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) (AA 50-100) antibodyCNOT4 适用: 人, 小鼠, 大鼠, Cow, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) antibodyCNOT4 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) (AA 539-588) antibodyCNOT4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) (Middle Region) antibodyCNOT4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-CCR4-NOT Transcription Complex Subunit 4 (CNOT4) (AA 61-110) antibodyCNOT4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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CNOT4 antibody can be used for detection of CNOT4 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- CNOT4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- CNOT4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- CNOT4 (CCR4-NOT Transcription Complex Subunit 4 (CNOT4))
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别名
- CNOT4
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背景
- CNOT4 Antibody: CNOT4 is a component of the CCR4-NOT transcription complex, a complex that is implicated in the repression of RNA polymerase II transcription. In the CCR4-NOT complex, CNOT4 acts as an E3 ubiquitin-protein ligase and interacts with a subset of E2 ubiquitin-conjugating enzymes through a unique C4C4 RING domain. This E3 ligase activity was shown to be dependent on the selective and specific interaction with the ubiquitin conjugating enzyme UbcH5B. In yeast, mutations in CNOT4 that prevented its interaction with the UbcH5B homolog UBC4 caused increased sensitivity to hydroxyurea, heat shock, and hygromycin B, suggesting that CNOT4 and UbcH5B are involved in stress response in vivo. Multiple isoforms of CNOT4 are known to exist.
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基因ID
- 4850
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NCBI登录号
- NP_037448
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UniProt
- O95628
抗原
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