AKIRIN2 抗体 (AA 80-130)
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北京 101111
Quick Overview for AKIRIN2 抗体 (AA 80-130) (ABIN6990981)
抗原
See all AKIRIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-130
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纯化方法
- Akirin2 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Akirin2 antibody was raised against a 15 amino acid synthetic peptide near the center of the human Akirin2. The immunogen is located within amino acids 80 - 130 of Akirin2.
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亚型
- IgG
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anti-Akirin 2 (AKIRIN2) (AA 1-203) antibody
AKIRIN2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3D9 unconjugated
anti-Akirin 2 (AKIRIN2) antibodyAKIRIN2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Akirin 2 (AKIRIN2) (AA 8-203) antibodyAKIRIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Akirin 2 (AKIRIN2) (AA 177-203), (C-Term) antibodyAKIRIN2 适用: 人 WB 宿主: 兔 Polyclonal RB36503 unconjugated
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应用备注
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Akirin2 antibody can be used for detection of Akirin2 by Western blot at 0.5 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Akirin2 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Akirin2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- AKIRIN2 (Akirin 2 (AKIRIN2))
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别名
- Akirin2
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背景
- Akirin2 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-κ,B-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-κ,B pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-α, and IL-1β, signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.
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基因ID
- 55122
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UniProt
- Q53H80
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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