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FERMT3 抗体 (C-Term)

FERMT3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990977
发货至: 中国
  • 抗原 See all FERMT3 抗体
    FERMT3 (Fermitin Family Member 3 (FERMT3))
    抗原表位
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, 大鼠
    宿主
    • 31
    • 4
    • 1
    • 1
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FERMT3 antibody is un-conjugated
    应用范围
    • 16
    • 13
    • 13
    • 10
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    KINDLIN3 Antibody is affinity chromatography purified via peptide column.
    免疫原
    KINDLIN3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of the human KINDLIN3. The immunogen is located within the last 50 amino acids of KINDLIN3.
    亚型
    IgG
    Top Product
    Discover our top product FERMT3 Primary Antibody
  • 应用备注
    KINDLIN3 antibody can be used for detection of KINDLIN3 by Western blot at 1 and 2 μ,g/mL.

    Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    KINDLIN3 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    KINDLIN3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    FERMT3 (Fermitin Family Member 3 (FERMT3))
    别名
    KINDLIN3 (FERMT3 产品)
    别名
    C79673 antibody, Kindlin3 antibody, RGD1310168 antibody, MGC69069 antibody, MGC88900 antibody, KIND3 antibody, MIG-2 antibody, MIG2B antibody, UNC112C antibody, URP2 antibody, URP2SF antibody, zgc:64101 antibody, fermitin family member 3 antibody, fermitin family member 3 L homeolog antibody, fermitin family member 3b antibody, Fermt3 antibody, fermt3.L antibody, fermt3 antibody, FERMT3 antibody, fermt3b antibody
    背景
    KINDLIN3 Antibody: The three KINDLINs are a novel family of focal adhesion proteins, localizing to integrin adhesion sites. The KINDLIN proteins are composed of a centrally located FERM domain interrupted by a pleckstrin homology (PH) domain. KINDLIN1 and KINDLIN2 have been shown to play an essential role in integrin-mediated adhesion and spreading. In contrast to the widely expressed KINDLIN1 and KINDLIN2, KINDLIN3 is restricted to hematopoietic cells and is particularly abundant in megakaryocytes and platelets. Several reports describe a transcriptional misregulation of KINDLINs in various types of cancer. A recent study demonstrates that KINDLIN3 is essential for platelet integrin activation and subsequent integrin outside-in signaling, suggesting it may serve as a potential target for the design of therapeutics aimed at specifically disrupting integrin activation in platelets and leukocytes.
    分子量
    Predicted: 73 kDa

    Observed: 73 kDa
    基因ID
    83706
    NCBI登录号
    NP_848537
    UniProt
    Q86UX7
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