Hax1a (N-Term) 抗体
This 兔 多克隆 antibody specifically detects Hax1a in ELISA 和 WB. It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN6990946
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Hax1a (N-Term) 抗体 (ABIN6990946)
抗原
Hax1a
适用
人, 大鼠, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- N-Term
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特异性
- At least four isoforms of Hax1 are known to exist. This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.
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纯化方法
- Hax1a Antibody is affinity chromatography purified via peptide column.
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免疫原
- Hax1a antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human Hax1a. The immunogen is located within the first 50 amino acids of Hax1a.
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亚型
- IgG
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应用备注
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Hax1a antibody can be used for detection of Hax1A by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Hax1a Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Hax1a antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Hax1a
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背景
- Hax1a Antibody: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting.
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基因ID
- 10456
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NCBI登录号
- NP_006109
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UniProt
- O00165
抗原
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