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NUP160 抗体 (C-Term)

This anti-NUP160 antibody is a 兔 多克隆 antibody detecting NUP160 in WB, ELISA, IHC (p) 和 IF. Suitable for 小鼠, 人 和 大鼠.
产品编号 ABIN6990945
发货至: 中国

Quick Overview for NUP160 抗体 (C-Term) (ABIN6990945)

抗原

See all NUP160 抗体
NUP160 (Nucleoporin 160kDa (NUP160))

适用

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小鼠, 人, 大鼠

宿主

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克隆类型

  • 47
多克隆

标记

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This NUP160 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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    C-Term

    纯化方法

    NUP160 Antibody is affinity chromatography purified via peptide column.

    免疫原

    NUP160 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human NUP160. The immunogen is located within the last 50 amino acids of NUP160.

    亚型

    IgG
  • 应用备注

    NUP160 antibody can be used for detection of NUP160 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NUP160 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    NUP160 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    NUP160 (Nucleoporin 160kDa (NUP160))

    别名

    NUP160

    背景

    NUP160 Antibody: The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.

    基因ID

    23279

    UniProt

    Q12769

    途径

    Protein targeting to Nucleus
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